Research Associate at Syngene for M.Sc Chemistry Candidates
Research Associate at Syngene for M.Sc chemistry candidates. MSc Chemistry Jobs. Syngene Research Jobs Chemistry. Interested and eligible applicants can check out all of the details on the same below:
Job position: Research Associate
Job Location: Bangalore
Department: Chemical Development- PRD
About Syngene
Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit
Mandatory expectation for all roles as per Syngene safety guidelines
- Overall adherence to safe practices and procedures of oneself and the teams aligned
- Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
- Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
- Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
- Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
- Compliance to Syngene’ s quality standards at all times
- Hold self and their teams accountable for the achievement of safety goals
- Govern and Review safety metrics from time to time
Role Purpose:
Performing activities at both lab and manufacturing facility to ensure the lab process safely transferred to pilot scale / commercial scale with reproducible results.
Key Responsibilities:
- Contribute individually (or as a team when appropriate) by performing experiments in lab and update laboratory notebook contemporaneously. Targeting minimum two experiments in a working day at lab
- Perform experiments to generate data for process robustness, plant simulation studies, process safety studies, etc.
- Record all minute observation while lab experimentations and transfer knowledge to execution team for flawless smooth execution.
- Synthesize reference standard, impurity markers, intermediates, and APIs to support method development in ADL and customers need from lab scale.
- Ensure effective utilization of the resources and tools for developing the process.
- Ensuring 100% compliance in safety, quality, data integrity and trainings.
- Generate projects documents like TTD, development report / campaign report
- Establish excellent interpersonal relationship with CFT for smooth execution
- Ensure individual contribution is met as per PRD guidelines
- Observe critically the batches while execution at manufacturing facility and provide valuable feedback to improve the process and avoid failure.
- Review the process documents like TTD, BMR, scale up studies, engineering studies, etc. to ensure the process is robust enough and all necessary data are available.
- Monitor the reactor days, batch input output data and collecting the analytical documents etc. pertaining to scale up batches
- Ensure flawless execution of scale up activities with 100% compliance on safety, quality and data integrity.
Education and Qualification for Research Associate at Syngene :
- M.Sc. Chemistry with 1 – 3 years of experience in PRD & Scale up.
TECHNICAL /FUNCTIONAL SKILLS:
- Basic synthetic organic chemistry knowledge with an ability to propose synthetic routes rapidly that is safe and scalable.
- Excellent process development skills to arrive at a process that is scalable in the kg scale.
- Experience in handling pyrophoric and moisture sensitive reagent.
- Sound knowledge in process analytical chemistry
- Proposing study plan for fit to purpose development studies.
- Strong analytical skills to derive trend, conclusion, and path forward, out of large set of data.
- Logical thinking and attention to details.
- Excellent written and verbal communication skills.
- Operational Excellence.
- Process Safety and GMP compliances
- Knowledge on required analytical techniques / tools
Other Responsibilities for Research Associate at Syngene
- Adherence to all procedures related to data integrity
- Ensure there is no violation of any environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety
- Understand and demonstrate the responsibility for safety of self & colleagues by following all necessary safety protocols at all times
- Identify near-misses and potential incidents proactively and communicate those
- Attend all assigned mandatory trainings related to data integrity, health, and safety measures
Equal Opportunity Employer for Research Associate at Syngene:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.
Possible interview questions answers may be asked for Research Associate at Syngene
- Can you describe your experience with process development in a laboratory setting?Answer: In my previous role, I was actively involved in process development for chemical compounds. I conducted experiments to optimize reactions and ensure scalability from the lab to pilot scale. This included synthesizing reference standards, impurity markers, and intermediates to support method development and customer requirements. I also documented all observations meticulously and maintained laboratory notebooks.
- How do you ensure compliance with safety, quality, and data integrity standards in your work Research ?Answer: I prioritize safety, quality, and data integrity in all aspects of my work. I strictly adhere to safety protocols, ensuring 100% compliance with safety guidelines and procedures. I maintain detailed records and follow Good Laboratory Practices (GLP) to uphold data integrity. Quality is maintained through rigorous adherence to quality standards, including reviewing process documents and ensuring robustness in scale-up studies.
- Can you provide an example of a challenging project you worked on in process development? How did you overcome the challenges?Answer: In a previous project, we faced challenges in optimizing a chemical process for scalability while maintaining product quality. To overcome this, I collaborated closely with cross-functional teams, including analytical chemistry and engineering. We conducted in-depth analyses of process data, identified critical parameters, and made necessary adjustments to ensure a successful scale-up while meeting quality standards.
- How do you approach the development of a scalable chemical process?Answer: Developing a scalable process involves a systematic approach. I start by proposing synthetic routes that are not only efficient but also safe and scalable. I consider factors like reagent sensitivity and moisture sensitivity. Additionally, I use process analytical chemistry to monitor reactions in real-time and make data-driven decisions. Logical thinking, attention to detail, and strong analytical skills play a crucial role in arriving at a scalable process.
- Can you describe your experience with process safety and GMP (Good Manufacturing Practices) compliances?Answer: I have a solid understanding of process safety principles and GMP compliances. I have experience working with pyrophoric and moisture-sensitive reagents, where safety precautions are paramount. Additionally, I ensure that all scale-up activities are conducted with 100% compliance on safety, quality, and data integrity. I am proactive in identifying potential safety hazards and taking preventive measures.
