MSc Pharmaceutical Sciences Jobs at Syngene – Apply For Invitro ADME Scientist Role
Title: Invitro ADME Scientist
Date: 5 Nov 2024
Job Location: Bangalore
Pay Grade: 9-II
Year of Experience: 1 – 4 Years
Designation: Invitro ADME Scientist
Job Location: Bangalore/Hyderabad
Department: Discovery Biology
About Syngene
Syngene (www.syngeneintl.com) is an innovation-led contract research, development, and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit.
Mandatory Expectation for All Roles as per Syngene Safety Guidelines
- Overall adherence to safe practices and procedures of oneself and the teams aligned.
- Contributing to the development of procedures, practices, and systems that ensure safe operations and compliance with the company’s integrity & quality standards.
- Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
- Ensuring safety of self, teams, and lab/plant by adhering to safety protocols and following EHS requirements at all times in the workplace.
- Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team, including self.
- Compliance to Syngene’s quality standards at all times.
- Hold self and their teams accountable for the achievement of safety goals.
- Govern and review safety metrics from time to time.
Job Purpose
Highly lab-based role, conducting metabolism, Phys-Chem, Caco-2, LLC-PK1-MDR1, MDCK-II-MDR1, MDCK-II BCRP transporter assays in 24 well/96 well plate trans well assays using different matrices with the highest quality.
Key Responsibilities:
- Design and execute Caco-2, LLC-PK1-MDR1, MDCK-II-MDR1, MDCK-II BCRP transporter assays in 24 well/96 well/384 well plate trans well assays.
- Able to handle Metabolism and Phys-Chem studies.
- Reporting of executed studies without mistakes.
- Raw data compilation, report preparation, and eLN updation on time.
- Presenting the study results clearly in cross-functional scientific meetings.
- Follow environment, health, and safety (EHS) requirements at all times in the workplace—ensuring individual and lab/plant safety.
- Ensure environment, health, and safety (EHS) measures are imparted via training and adhered to within the team.
Educational Qualification:
- M Pharm. in any pharmaceutical science or M Sc. in biological science.
Technical/Functional Skills:
- Comprehensive understanding of in vitro ADME assays and technical expertise in troubleshooting the assays.
- Experience in conducting cell-based assays using wild-type and transporter transfected cell lines.
- Good, demonstrated knowledge in software such as Microsoft Excel and GraphPad Prism.
- Report preparation and review of reports ready to share with clients.
- Understanding the functionality, operation, and maintenance of instruments (TEER inst, Microscope, biosafety cabinet, LN2, etc.).
Experience:
- M Pharm. in pharmaceutical sciences or M Sc. in biological science with one to four years of industrial experience in DMPK/ADME research.
Behavioral Skills:
- Demonstrate ability to be a team player.
- Commitment to deliver study reports within the agreed timelines.
- Adaptability to changes in the dynamic lab environment.
- Communicate confidently with colleagues and collaborators in meetings and presentation of study reports.
- Evidence of publications in peer-reviewed journals.
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