U.S. Pharmacopeial Convention (USP)
The U.S. Pharmacopeial Convention (USP) is a scientific nonprofit organization that sets standards for the identity, strength, quality, and purity of medicines, food ingredients, and dietary supplements manufactured, distributed and consumed worldwide. USP’s drug standards are enforceable in the United States by the Food and Drug Administration, and these standards are used in more than 140 countries. This is a hands-on non-supervisory position in the Compendial Development Laboratory (CDL) within Global Laboratory Operations. The incumbent will be responsible for the development and validation of the documents standards using multiple source ingredients and products while maintaining GLP and safe practices. This position is a component of USP’s core business and the incumbent is expected to support monograph modernization initiatives.
Job Title:Â Â Â Scientist II
Tracking Code :Â 1057-679
Job Description:
This is a non-supervisory position responsible for the synthesis, scale-up, purification and characterization of API impurities on milligram-to-multigram scale. The incumbent in this role will plan and execute diverse synthetic schemes to produce reference materials for supporting organizational business initiatives and RS material production.
Roles and Responsibilities:
- Responsible for carrying out literature search using various scientific data bases such as SciFinder and Reaxys, and design synthetic schemes to prepare target molecules
- Responsible for the making project proposals with cost estimate
- Perform wide range of critical reactions involving air sensitive and moisture sensitive reagents to synthesize desired compounds
- Optimize reaction conditions and apply purification procedures to produce quality products as per specifications
- Characterization of compounds based on analytical data such as IR, NMR, Mass Spectra
- Documentation of experiments conducted and the observation made as per QA guidelines
- Follow personal and lab safety guidelines
Qualifications:Â
Required Skills
- M.Sc in Organic chemistry with not less than 4-6 years of work experience in CRO or Pharmaceutical Process R&D, or NCE R&D.
- Hands on experience in the synthesis, purification and characterization of wide range of organic compounds
- Expertize in designing synthetic routes for any given target molecule
- Ability to carry literature search using scientific databases – Scifinder,and Reaxys etc
Required Experience
- Sound knowledge in Synthetic organic chemistry and excellent troubleshooting skills
- Track record of producing structurally diverse compounds including heterocycles and macrolides
- Ability to work in a cross functional team environment
