Aurigene
Aurigene is a specialized biotech company committed to the vision of being the most respected and valued biotech in India. Focused on oncology and inflammatory diseases, Aurigene has applied its deep target and therapeutic area expertise, gained from the experience of multiple programs, to deliver both small molecule and peptide drug candidates to its biotech and pharmaceutical partners. Aurigene has pioneered a unique model of Drug Discovery collaborations with large-pharmaceutical, mid-pharmaceutical companies and biotechs
Job Title: Research Associate – DMPK
No. of Posts: 1
Job Description:
In-vitro Studies
- Prepare and review work procedures, study reports, protocols and SOPs with clarity, consistency, scientific correctness and applicable industry best practices. n-vitro Studies
- Perform cell based permeability assays including the transport assay, preparation of stocks, revival, sub-culturing, seeding and maintenance of CaCo2 & MDCK cell lines.
- Conduct transporter and cytotoxicity assays with primary hepatocytes, hepaRG cells and other cell lines.
In-vivo Studies
- Execution of in-vivo preclinical pharmacokinetic studies in rodents.
- Execution of in-vivo tissue distribution & mass balance studies in rodents.
- Bioanalysis of the samples from in-vivo pharmacokinetic & tissue distribution studies through LCMS/MS.
- Bioanalysis of the samples from maximum tolerated dose, efficacy, PKPD & TK studies through LSMS/MS.
- To execute the analysis of dose formulations through HPLC.
- Pharmacokinetic studies in mice and rat. Understanding of systems and process pertaining to safety, health and environment.
Competencies:
- Trouble-shooting ability
- Good Communication Skills- both written & verbal
- Well versed with MS Office applications
- Multi-tasking capabilities
- Team Player
Qualifications: M. Pharm (Pharmacology)/M.Sc. (Biotechnology, Biochemistry, Biosciences) with 1-6 years of experience.
General Terms and Conditions:
Application Instructions : Please send your profile at [email protected]
