Shiv Nadar University Vacancies - Chemistry Jr Research Fellow

Shiv Nadar University Vacancies – Chemistry Jr Research Fellow

Applications are invited for the post of Junior Research Fellow (JRF) in a DST funded research project entitled “Development of Palladium-Catalyzed Triple Cascade for the Synthesis of Tetracyclic Core of Apocynaceae Family of Indole Alkaloids”

Principal Investigator:

under the supervision of Dr. Ajoy Kapat, Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Gautam Buddha Nagar, U.P. 201314. E-mail: [email protected]

Web: https://chemistry.snu.edu.in/people/faculty/ajoy-kapat

Job Title: Junior Research Fellow

Job Id: 253

Department: Chemistry

Job Type: Contract

No. of Positions: 1

Project Synopsis

Development of palladium-catalyzed triple cascade reaction to have very efficient access of tetracyclic core of Apocynaceae family of indole alkaloids. The major objectives are:

Objectives

  • To develop a palladium-catalyzed domino reaction for the synthesis of the tricyclic core using 1,2-dihalocyclohexene utilizing domino N-H/C-H bond functionalization.
  • To extend this methodology for the development of the triple cascade to synthesize tetracyclic core of Apocynaceae family of alkaloids.
  • Application of the double/triple cascade reaction in total synthesis of Apocynaceae family of indole alkaloids.
  • A detailed mechanistic study utilizing modern experimental techniques to understand the reaction mechanism in detail.
  • To study biological activities of the Apocynaceae family of indole alkaloids.

Nature of work

Identification of new target molecules showing anti-viral activity against Flaviviridae, Flaviviruses, pestiviruses, and hepaciviruses. Discovery of new molecules, which can be used for the treatment of dengue fever, yellow fever, west nile virus, and hepatitis C virus. The first part involves the development of an efficient synthetic strategy applying transition metal-catalyzed cascade reaction to synthesize a library of compounds and the second part involves evaluation of the biological activity of these compounds.

Essential and Desirable Qualifications

  • The candidate should have a Master’s degree (with a minimum of 55% marks or equivalent grade) in Chemistry (Organic/Inorganic) from a UGC-recognized University or Institutions.
  • The candidate should have good analytical and communication skills.
  • Familiarity with organic synthesis and characterizations will be preferred.
  • Understanding of reaction mechanism of organic and organometallic reactions is desirable.
  • Candidates with CSIR/UGC-NET/JEST/GATE are encouraged to apply.

Duration of the Project

1 year (purely temporary), can be extended further based on satisfactory performance in the first year.

Fellowship

As per DST norms, fellowship is ₹31,000/- p.m. plus HRA for JRF

How To Apply:

Eligible and interested candidates should submit their application with a complete CV (having personal and academic details, academic qualifications, research experiences, publications, name, affiliation, and email address of at least two referees) to Dr. Ajoy Kapat ([email protected]). The copies of mark sheets/ testimonials/ certificates, a recent passport size photograph, and other relevant documents are also required.

Application deadline: 18 Sep 2021

Apply Online

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