Shiv Nadar University Vacancies – Chemistry Jr Research Fellow
Applications are invited for the post of Junior Research Fellow (JRF) in a DST funded research project entitled “Development of Palladium-Catalyzed Triple Cascade for the Synthesis of Tetracyclic Core of Apocynaceae Family of Indole Alkaloids”
Principal Investigator:
under the supervision of Dr. Ajoy Kapat, Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Gautam Buddha Nagar, U.P. 201314. E-mail: [email protected]
Web: https://chemistry.snu.edu.in/people/faculty/ajoy-kapat
Job Title: Junior Research Fellow
Job Id: 253
Department: Chemistry
Job Type: Contract
No. of Positions: 1
Project Synopsis
Development of palladium-catalyzed triple cascade reaction to have very efficient access of tetracyclic core of Apocynaceae family of indole alkaloids. The major objectives are:
Objectives
- To develop a palladium-catalyzed domino reaction for the synthesis of the tricyclic core using 1,2-dihalocyclohexene utilizing domino N-H/C-H bond functionalization.
- To extend this methodology for the development of the triple cascade to synthesize tetracyclic core of Apocynaceae family of alkaloids.
- Application of the double/triple cascade reaction in total synthesis of Apocynaceae family of indole alkaloids.
- A detailed mechanistic study utilizing modern experimental techniques to understand the reaction mechanism in detail.
- To study biological activities of the Apocynaceae family of indole alkaloids.
Nature of work
Identification of new target molecules showing anti-viral activity against Flaviviridae, Flaviviruses, pestiviruses, and hepaciviruses. Discovery of new molecules, which can be used for the treatment of dengue fever, yellow fever, west nile virus, and hepatitis C virus. The first part involves the development of an efficient synthetic strategy applying transition metal-catalyzed cascade reaction to synthesize a library of compounds and the second part involves evaluation of the biological activity of these compounds.
Essential and Desirable Qualifications
- The candidate should have a Master’s degree (with a minimum of 55% marks or equivalent grade) in Chemistry (Organic/Inorganic) from a UGC-recognized University or Institutions.
- The candidate should have good analytical and communication skills.
- Familiarity with organic synthesis and characterizations will be preferred.
- Understanding of reaction mechanism of organic and organometallic reactions is desirable.
- Candidates with CSIR/UGC-NET/JEST/GATE are encouraged to apply.
Duration of the Project
1 year (purely temporary), can be extended further based on satisfactory performance in the first year.
Fellowship
As per DST norms, fellowship is ₹31,000/- p.m. plus HRA for JRF
How To Apply:
Eligible and interested candidates should submit their application with a complete CV (having personal and academic details, academic qualifications, research experiences, publications, name, affiliation, and email address of at least two referees) to Dr. Ajoy Kapat ([email protected]). The copies of mark sheets/ testimonials/ certificates, a recent passport size photograph, and other relevant documents are also required.
Application deadline: 18 Sep 2021
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