SNU MSc Chemistry JRF Recruitment 2020 – Application Details
Applications are invited for the post of Junior Research Fellow (JRF) in a DST funded research project entitled “Development of Palladium-Catalyzed Triple Cascade for the Synthesis of Tetracyclic Core of Apocynaceae Family of Indole Alkaloids” under the supervision of Dr. Ajoy Kapat, Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Gautam Buddha Nagar, U.P. 201314. E-mail: [email protected]
Job Title: Junior Research Fellow (JRF)
Job Id: 218
Department: Chemistry
Job Type: Contract
Job Description
Web: https://chemistry.snu.edu.in/people/faculty/ajoy-kapat
Project Synopsis
Development of palladium-catalyzed triple cascade reaction to have very efficient access of tetracyclic core of Apocynaceae family of indole alkaloids.The major objectives are:
Objectives
- To develop a palladium-catalyzed domino reaction for the synthesis of tricyclic core using 1,2-dihalocyclohexene utilizing domino N-H/C-H bond functionalization.
- To extend this methodology for the development of the triple cascade to synthesize tetracyclic core of Apocynaceae family of alkaloids.
- Application of the double/triple cascade reaction in the total synthesis of Apocynaceae family of indole alkaloids.
- A detailed mechanistic study utilizing modern experimental techniques to understand the reaction mechanism in detail.
- To study biological activities of the Apocynaceae family of indole alkaloids.
Nature of work
Identification of new target molecules showing anti-viral activity against Flaviviridae, Flaviviruses, pestiviruses, and hepaciviruses. Discovery of new molecules, which can be used for the treatment of dengue fever, yellow fever, west nile virus, and hepatitis C virus. First part involve the development of an efficient synthetic strategy applying transition metal-catalyzed cascade reaction to synthesize a library of compounds and the second part involves evaluation of the biological activity of these compounds.
Essential and Desirable Qualifications
- The candidate should have a Master’s degree (with a minimum of 55% marks or equivalent grade) in Chemistry (Organic/Inorganic) from a UGC recognized University or Institutions.
- The candidate should have good analytical and communication skills. Familiarity with organic synthesis and characterizations will be preferred.
- Understanding of reaction mechanism of organic and organometallic reactions is desirable.
- Candidates with CSIR/UGC-NET/JEST/GATE are encouraged to apply.
Duration of the Project
1 year (purely temporary), can be extended further based on satisfactory performance in the first year.
Fellowship
As per DST norms, fellowship is ₹31,000/- p.m. plus HRA for JRF
How To Apply:
Eligible and interested candidates should submit their application with a complete CV (having personal and academic details, academic qualifications, research experiences, publications, name, affiliation, and email address of at least two referees) to Dr. Ajoy Kapat ([email protected]). The copies of mark sheets/ testimonials/ certificates, a recent passport size photograph, and other relevant documents are also required.
Short-listed candidates will be contacted for the online interview.
Application deadline: 09 Jan 2021
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